MCMP 208 - Biochemistry For Pharmaceutical Sciences I

Spring Semester 2017
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Educational Expectations for Students Entering into MCMP 208

Make sure to reveiw and understand these.

General and Organic Chemistry
Stereochemistry
pH
Ionization of organic acids and bases (including amides and alcohols), pKa, Henderson-Hasselbach equation
Keto-enol tautomerization
Amides: nature, make up, hyrdolysis
Esters, phosphoesters, phosphodiesters
Chemical equlibria and Keq
ΔG (change in Gibbs free energy) of a reaction
Covalent versus non-covalent chemical bonds, including dipole and ionic non-covalent bonds
Binding (chelation) reactions, forces, and equilibria
Organic sulphides (thiols), disulphides
Reaction progress, energy of activation, and catalysis
General Acid-Base catalysis
Reaction kinetics, simple rate expressions
Nitrogen heterocycles
Non-covalent forces: pi-orbital bonding, hydrophobic, polar, and ionic
General polymer concepts (what they are, linear vs branched/cross-linked)
The (non-radical) oxidized states of carbon and their neutral forms (methane/methylene, methanol/alcohol, etc. up to carbon dioxide)
Anatomy and Phsyiology
The endocrine system including the principal hormones
Hormone receptors - general concepts
General Biology
Cellular anatomy (cell organelles and their roles)
The Cell cycle including its component phases
Genes and inheritance
Evolution in general, genetic mutants/variants
Chromosomes

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