Kinam Park, Ph.D. Showalter Distinguished Professor of Biomedical Engineering & Professor of Pharmaceutics Purdue University (BME Office) BMED Building, 206 S. Intramural Drive, West Lafayette, IN 47907. Tel: 765) 494-7759 (IPPH Office) IPPH Annex, 1205 Kent Ave., West Lafayette, IN 47906. Tel: 765) 463-1989, x115 E-mail: kpark@purdue.edu B.S. in Pharmacy, Seoul National University, 1971-75 Lieutenant in the Korean Army, 1975-1977 Ph.D. in Pharmaceutics, University of Wisconsin, 1979-83 Postdoc in Chem. Eng., University of Wisconsin, 1983-85

Teaching

• IPPH 690W (BME 695K): Polymers in Pharmaceutical & Biomedical Systems
  Course Outline
  1. Introduction to Polymers
  2. Polymer Synthesis & Polymer Properties
  3. Polymers in Biomaterials
  4. Polymers in Biotechnology
  5. Smart Polymers & Hydrogels
  6. Polymers in Pharmaceutics
  7. Polymers in Nanotechnology
  8. Polymers in Tissue Engineering and Cell Delivery
  9. Presentations on Polymer-related Topics

Research Interests

1. Drug/polymer coating for drug-eluting stents

2. Nanofabrication and micromanufacturing of nano/microparticles

3. Hydrotropic polymer micelles for delivery of poorly soluble drugs

4. Fast dissolving tablets

5. Superporous hydrogels

Books Published

1)   Park, K., Shalaby, S.W.S., and Park, H.: Biodegradable Hydrogels for Drug Delivery, Technomic Publishing Co., Inc., Lancaster, PA, 1993, 252 pages.

2)   Ottenbrite, R., Hwang, S., and Park, K., Eds.: Hydrogels and Biodegradable Polymers for Bioapplications (ACS Symposium Series 627), American Chemical Society, Washington, DC, 1996, 268 pages.

3)   Park, K., Ed.: Controlled Drug Delivery: Challenges and Strategies, American Chemical Society, Washington, DC, 1997, 629 pages.

4)   Park, K. and Mrsny, R., Eds.: Controlled Drug Delivery: Designing Technologies for the Future (ACS Symposium Series 752), American Chemical Society, Washington, DC, 2000, 459 pages.

5)   Park, K.D., Kwon, I.C., Yui, N., Jeong, S.Y. and Park, K., Eds.: Biomaterials and Drug Delivery toward New Millennium, Han Rim Won Publishing Co., Seoul, Korea, 2000, 691 pages.

6)   Park, K. Ed., Protein- and Cell-Repellent Surfaces, Colloids and Surfaces B: Biointerfaces, Elsevier Science, Vol. 18 (No. 3-4), 2000.

7)   Park, K., Ed., Recent Developments in Hydrogels, Advanced Drug Delivery Reviews, Elsevier Science,Vol. 54, 2001.

8)   Yui, N. and Park, K., Eds.: Flash polymers and hydrogels: Understanding and designing the fast-responsive polymeric systems, CRC Press, Boca Raton, FL, 2004. 452 pages.

Journal Activity

Editor-in-Chief: Journal of Controlled Release

Selected Publications

Kinam Park : Nanotechnology: What it can do for drug delivery, J. Control. Release, 120: 1-3, 2007.

Eunah Kang, Joshua Robinson, and Kinam Park, and Ji-Xin Cheng: Paclitaxel distribution in poly(ethylene glycol) / poly(lactide-coglycolic acid) blends and its release visualized by coherent anti-Stokes Raman scattering microscopy, J. Control. Release, 122: 261-268, 2007.

Eunah Kang, Haifeng Wang , Il Keun Kwon, Young-Ho Song, Kalpana Kamath, Kathleen M. Miller, James Barry, Ji-Xin Cheng, and Kinam Park : Application of coherent anti-Stokes Raman scattering microscopy to image the changes in a paclitaxel-poly(styrene-b-isobutylene-b-styrene) matrix pre and post drug elution, J. Biomed. Mater. Res., in press.

Seong Hoon Jeong, Nahor Haddish Berhane, Kamyar Haghighi, and Kinam Park : Drug release properties of polymer coated ion-exchange resin complexes: Experimental and theoretical evaluation, J. Pharm. Sci., 96: 618-632, 2007.

Hong Wen, Ken Morris, and Kinam Park : Synergic Effects of Polymeric Additives on Dissolution and Crystallization of Acetaminophen, Pharm. Res., in press.

Connie Snider, Sang-Youp Lee, Yoon Yeo, Gérald J. Grégori, J. Paul Robinson, and Kinam Park : Microenvironment-controlled encapsulation (mice) process: effects of plga concentration, flow rate, and collection method on microcapsule size and morphology, Pharm. Res., in press

Sang Cheon Lee, Kang Moo Huh, Jaehwi Lee, Yong Woo Cho, Raymond E. Galinsky, and Kinam Park : Hydrotropic Polymeric Micelles for Enhanced Paclitaxel Solubility: In Vitro and In Vivo Characterization, Biomacromolecules, 8: 202-208, 2007.

Kang Moo Huh, Hyun Soo Mi, Sang Cheon Lee, Hong Jae Lee, Sungwon Kim, Kinam Park : A new hydrotropic block copolymer micelle system for aqueous solubilization of paclitaxel, J. Control. Release, in press.

Graduate Students and Postdocs

Mingli Ye

Kumar Vedantham

Samali Chaterji

Ji-Young Kim

Jutarat Kitsongsermthon

Yuuki Takaishi

Sungwon Kim , Ph.D.

Jong-Ho Kim, Ph.D.

Oju Jeon, Ph.D.