Issued patents:
1. Leary, J.F., Todd, P.: "Pulse Edge Measurements for Determining Particle Dimensional Characteristics" U.S. Patent 4,263,508 (1981). (high resolution time-of-flight, real-time cell size and shape analysis)
2-3. Leary, J.F., Corio, M.A., McLaughlin, S.R. “System for High-Speed Measurement and Sorting of Particles” U.S. Patents 5,204,884 (1993) and 5,804,143 (1998). (ultra high-speed flow cytometry/sorting)
4-6. Corio, M.A.., Leary, J.F. "System for Flexibly Sorting Particles" U.S. Patents 5,199,576(1993 ) and 5,550,058 (1996) and 5,998,212 (1999). (sophisticated real-time algorithms for cell sorting and neural network sorting architecture)
7. Leary, J.F. “Subtractive Clustering for Use in Analysis of Data” (advanced data mining algorithms for comparing two or more large multidimensional data sets) U.S. Patent 7,043,500 (2006).
8. Leary, J.F., Frederickson, C.J. “Flow Sorting System and Methods Regarding Same” U.S. Patent 7,452,725 (2008). (high-speed microfluidic sorting fluidic architectures for portable cell sorting)
9. Gorenstein, D.G. Luxon, B.A., Herzog, N.K., Yang, X-B, Aronson, J.F., Shope, R., Beasley, D., 8. Barrett, A.D., Leary, J.F. Structure-based and combinatorially selected oligonucleoside phosphorothioate and phosphorodithioate aptamers targeting AP-1 transcription factors. U.S. Patent 7,910,523 (2011).
10. Lelievre, S.A., Vidi, P-A., Leary, J.F., Maleki, T., “Disease on a Chip” US Patent 9,969,964 (2018)
(This patent relates to the mimicking of human disease and normal tissue using 3D scaffolds and microfluidic chips collectively called “organ-on-a-chip” technologies to grow new artificial human organs in 3D tissue culture. This allows for the rapid testing of new therapies on human cells rather than in animals thereby accelerating clinical trials).
Other patent actions:
1. Leary, J.F. and Prow, T.W. Multilayered Nanomedicine Delivery System and Method PCT/US05/06692 on 3/4/2005. (multilayered, programmable nanoparticle drug delivery systems with biosensor feedback control)
2. Leary, JF, Park, K., Acharya, G. Aronson, A., Zordan, M. Hybrid SPR/Molecular Imaging Microfluidic Device for Detection of Pathogens. Full International Patent PCT/US08/81571 (filed October 29, 2008)
3. Leary, J.F., Eustaquio, T. "Single nanoparticle detection by DNA barcoding for biodistribution studies in nanomedicine" U.S. Patent Application No. 61/363,898 (2010).
4. Zordan, M.D., Leary, J.F. "Image and Data Analysis for Wound Healing Assay". U.S. Patent Application No. 61/332,399 (filed 5/14/2010).
5. Reece, L.M., Thakur, R., Alucozai, M., Leary, J.F. “Aneurysm-on-a-Chip™ Microfluidics Device”. Purdue Office of Technology Commercialization Disclosure: 2013-REEC-66567 (2013).
Last updated on Janiary 5, 2022