Selected Publications

Kargl CK, Jia Z, Shera DA, Sullivan BP, Burton LC, Nie Y, Jubal MJ, Shannahan JH, Kuang S, Gavin TP. 2023. Angiogenic potential of skeletal muscle derived extracellular vesicles differs between oxidative and glycolytic muscle tissue. Sci Rep. 13(1):18943.

You W, Xu Z, Chen W, Yang X, Liu S, Wang L, Tu Y, Zhou Y, Valencak TG, Wang Y, Kuang S, Shan T. 2023. Cellular and transcriptional dynamics during brown adipose tissue regeneration under acute injury. Research.

Kim KH, Oprescu SN, Snyder MM, Kim A, Jia Z, Yue F, Kuang S. PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors. Cell Rep. 42(11):113329.

Qiu J, Yue F, Zhu P, Chen J, Xu F, Zhang L, Kim KH, Snyder MM, Luo N, Xu H, Huang F, Tao WA, Kuang S. 2023. FAM210A is essential for cold-induced mitochondrial cristae remodeling in brown adipocytes. Nat Commun. 14(1):6344.

Wang Y, Troughton LD, Xu F, Chatterjee A, Zhao H, Cifuentes LP, Wagner RB, Chen J, Kuang S, Suter DM, Yuang C, Chan D, Huang F, Oakes PW, Deng Q. Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells. eLife.

Oprescu SN, Baumann, N, Chen X, Zhao Y, Yue F, Wang H. Kuang S. Sox11 is enriched in myogenic progenitors but dispensable for development and regeneration of the skeletal muscle. Skelet Muscle.

Ma Y, Wang HH, Hua Y, Kuang S. 2023. The Rise of Meat Substitute Consumption and its Impact on the U.S. Soybean Industry. Purdue Agricultural Economics Report. PAER-2023-25.

Kim KH, Jia Z, Snyder MM, Chen J, Qiu J, Oprescu SN, Chen X, Yue F, Roseguini BT, Imbalzano AN, Hu C, Kuang S. 2023. PRMT5 links lipid metabolism to contractile function of skeletal muscles. Embo Rep. e57306.

Tien PC, Chen X, Elzey BD, Pollock RE, Kuang S. Notch signaling regulates a metabolic switch through inhibiting PGC-1α and mitochondrial biogenesis in dedifferentiated liposarcoma. Oncogene.

Wang L, Gao P, Li C, Q Liu, Yao Z, Li Y, Zhang X, Sun J, Simintiras C, Welborn M, McMillin K, Oprescu S, Kuang S, Fu X. 2023. A single-cell atlas of bovine skeletal muscle reveals mechanisms underlying fatty infiltration in Wagyu muscle. J Cachexia, Sarcopenia Muscle.

Chen X, CR Ferreira, Kuang S. 2023. Targeted lipid profiling of adipose and skeletal muscle tissues. Methods Mol Biol. 2640:351-368

Unsihuay D, Hu H, Qiu J, Latorre-Palomino A, Yang M, Yue F, Yin R, Kuang S, Laskin J. 2023. Multimodal high-resolution nano-DESI MSI and immunofluorescence imaging reveal molecular signatures of individual skeletal muscle myofibers. Chemical Science, 14: 4070

Kargal CK, Sullivan BP, Middleton D, York A, Burton L, Brault JJ, Kuang S, Gavin TP. 2023. Peroxisome proliferator-activated receptor γ coactivator 1-α overexpression improves angiogenic signaling potential of skeletal muscle-derived extracellular vesicles. Exp Physiol. 108:240-52.

Ma Z, Huang Z, Zhang C, Liu X, Zhang J, Shu H, Ma Y, Liu Z, Feng Y, Chen X, Kuang S, Zhang Y, Jia Z. 2023. Hepatic Acat2 overexpression promotes systemic cholesterol metabolism and adipose lipid metabolism in mice. Diabetologia. 66:390-405.

Chen, J., Yue, F., & Kuang, S. (2022). Labeling and analyzing lipid droplets in mouse muscle stem cells. STAR protocols, 3(4), 101849.

Huang, K., Jia, Z., Li, H., Peng, Y., Chen, X., Luo, N., ... Kuang, S., & Yang, G. (2022). Proto-oncogene FAM83A contributes to casein kinase 1-mediated mitochondrial maintenance and white adipocyte differentiation. Journal of Biological Chemistry, 102339.

Garner, R. T., Weiss, J. A., Nie, Y., Sullivan, B. P., Kargl, C. K., Drohan, C. J., Kuang, S., ... & Gavin, T. P. (2022). Effects of obesity and acute resistance exercise on skeletal muscle angiogenic communication pathways. Experimental Physiology.

Chang, Y., Syahirah, R., Oprescu, S. N., Wang, X., Jung, J., Cooper, S. H., Torregrosa-Allen, S. , Elzey, B. D., Hsu, A. Y., Randolph, L. N., Sun, Y., Kuang, S.,... & Bao, X. (2022). Chemically-defined generation of human hemogenic endothelium and definitive hematopoietic progenitor cells. Biomaterials, 285, 121569.

Sullivan, B. P., Nie, Y., Evans, S., Kargl, C. K., Hettinger, Z. R., Garner, R. T., Hubal M. J., Kuang, S., ... & Gavin, T. P. (2022). Obesity and exercise training alter inflammatory pathway skeletal muscle small extracellular vesicle microRNAs. Experimental Physiology, 107(5), 462-475.

Xia, W., Qiu, J., Peng, Y., Snyder, M. M., Gu, L., Huang, K., ... & Kuang, S. (2022). Chchd10 is dispensable for myogenesis but critical for adipose browning. Cell Regeneration, 11(1), 1-15.

Yue, F., Oprescu, S. N., Qiu, J., Gu, L., Zhang, L., Chen, J., ... & Kuang, S. (2022). Lipid droplet dynamics regulate adult muscle stem cell fate. Cell Reports, 38(3), 110267.

Jia Z, Chen X, Chen J, Zhang L, Oprescu SN, Luo N, Xiong Y, Yue F, Kuang S. 2022. ACSS3 in brown fat drives propionate metabolism and its deficiency leads to autophagy and systemic metabolic dysfunction. Clin Transl Med. In press. IF: 11.5

Snyder, M. M., Yue, F., Zhang, L., Shang, R., Qiu, J., Chen, J., ... & Kuang, S. (2021). LETMD1 is required for mitochondrial structure and thermogenic function of brown adipocytes. The FASEB Journal, 35(11), e21965.

Huang, X., Kuang, S., Applegate, T. J., Lin, T. L., & Cheng, H. W. (2021). Prenatal Serotonin Fluctuation Affects Serotoninergic Development and Related Neural Circuits in Chicken Embryos. Neuroscience, 473, 66-80.

Hettinger, Z. R., Kargl, C. K., Shannahan, J. H., Kuang, S., & Gavin, T. P. (2021). Extracellular vesicles released from stress‐induced prematurely senescent myoblasts impair endothelial function and proliferation. Experimental Physiology, 106(10), 2083-2095.

Peng, Y., Yue, F., Chen, J., Xia, W., Huang, K., Yang, G., & Kuang, S. (2021). Phosphatase orphan 1 inhibits myoblast proliferation and promotes myogenic differentiation. The FASEB Journal, 35(1), e21154.

Narayanan, N., Jia, Z., Kim, K. H., Kuang, L., Lengemann, P., Shafer, G., ... & Deng, M. (2021). Biomimetic glycosaminoglycan-based scaffolds improve skeletal muscle regeneration in a Murine volumetric muscle loss model. Bioactive materials, 6(4), 1201-1213.

Yue, F., Song, C., Huang, D., Narayanan, N., Qiu, J., Jia, Z., ... & Kuang, S. (2021). PTEN inhibition ameliorates muscle degeneration and improves muscle function in a mouse model of Duchenne muscular dystrophy. Molecular Therapy, 29(1), 132-148.

Narayanan, N., Lengemann, P., Kim, K. H., Kuang, S., Sobreira, T., Hedrick, V., ... & Deng, M. (2021). Harnessing nerve–muscle cell interactions for biomaterials‐based skeletal muscle regeneration. Journal of Biomedical Materials Research Part A, 109(3), 289-299.

Unsihuay, D., Su, P., Hu, H., Qiu, J., Kuang, S., Li, Y., ... & Laskin, J. (2021). Imaging and analysis of isomeric unsaturated lipids through online photochemical derivatization of carbon–carbon double bonds. Angewandte Chemie, 133(14), 7637-7641.

Luo, N., Yue, F., Jia, Z., Chen, J., Deng, Q., Zhao, Y., & Kuang, S. (2021). Reduced electron transport chain complex I protein abundance and function in Mfn2‐deficient myogenic progenitors lead to oxidative stress and mitochondria swelling. The FASEB Journal, 35(4), e21426.

Jia, Z., Yue, F., Chen, X., Narayanan, N., Qiu, J., Syed, S. A., ... & Kuang, S. (2020). Protein Arginine Methyltransferase PRMT5 Regulates Fatty Acid Metabolism and Lipid Droplet Biogenesis in White Adipose Tissues. Advanced Science, 7(23), 2002602.

Huang, D., Yue, F., Qiu, J., Deng, M., & Kuang, S. (2020). Polymeric nanoparticles functionalized with muscle-homing peptides for targeted delivery of phosphatase and tensin homolog inhibitor to skeletal muscle. Acta Biomaterialia, 118, 196-206.

Sullivan, B. P., Weiss, J. A., Nie, Y., Garner, R. T., Drohan, C. J., Kuang, S., ... & Gavin, T. P. (2020). Skeletal muscle IGF-1 is lower at rest and after resistance exercise in humans with obesity. European Journal of Applied Physiology, 120(12), 2835-2846.

Tien, P. C., Quan, M., & Kuang, S. (2020). Sustained activation of notch signaling maintains tumor-initiating cells in a murine model of liposarcoma. Cancer Letters, 494, 27-39.

Quan, M., & Kuang, S. (2020). Exosomal Secretion of Adipose Tissue during Various Physiological States. Pharmaceutical Research, 37(11), 1-13.

Huang, D., Qiu, J., Kuang, S., & Deng, M. (2020). In Vitro Evaluation of Clinical Candidates of γ-Secretase Inhibitors: Effects on Notch Inhibition and Promoting Beige Adipogenesis and Mitochondrial Biogenesis. Pharmaceutical Research, 37(10), 1-13.

Kim, K. H., Qiu, J., & Kuang, S. (2020). Isolation, Culture, and Differentiation of Primary Myoblasts Derived from Muscle Satellite Cells. Bio-protocol, 10(14), e3686-e3686.

Oprescu, S. N., Yue, F., & Kuang, S. (2020). Single-Cell Isolation from Regenerating Murine Muscles for RNA-Sequencing Analysis. STAR Protocols, 1(2), 100051.

Huff, K., Suárez-Trujillo, A., Kuang, S., Plaut, K., & Casey, T. (2020). One-to-one relationships between milk miRNA content and protein abundance in neonate duodenum support the potential for milk miRNAs regulating neonate development. Functional & Integrative Genomics, 20, 645-656.

Huang, D., Narayanan, N., Cano-Vega, M. A., Jia, Z., Ajuwon, K. M., Kuang, S., & Deng, M. (2020). Nanoparticle-mediated inhibition of Notch signaling promotes mitochondrial biogenesis and reduces subcutaneous adipose tissue expansion in pigs. Iscience, 23(6), 101167.

Narayanan, N., Jiang, C., Wang, C., Uzunalli, G., Whittern, N., Chen, D., ..., Kuang, S., & Deng, M. (2020). Harnessing Fiber Diameter-Dependent Effects of Myoblasts Toward Biomimetic Scaffold-Based Skeletal Muscle Regeneration. Frontiers in bioengineering and biotechnology, 8, 203.

Oprescu, S. N., Yue, F., Qiu, J., Brito, L. F., & Kuang, S. (2020). Temporal dynamics and heterogeneity of cell populations during skeletal muscle regeneration. Iscience, 23(4), 100993.

Kim, K., Reid, B. A., Casey, C. A., Bender, B. E., Ro, B., Song, Q., ..., Kuang, S., Gavin, T., & Roseguini, B. T. (2020). Effects of repeated local heat therapy on skeletal muscle structure and function in humans. Journal of Applied Physiology, 128(3), 483-492.

Garner, R. T., Solfest, J. S., Nie, Y., Kuang, S., Stout, J., & Gavin, T. P. (2020). Multivesicular body and exosome pathway responses to acute exercise. Experimental Physiology, 105(3), 511-521.

Unsihuay, D., Qiu, J., Swaroop, S., Nagornov, K. O., Kozhinov, A. N., Tsybin, Y. O., ... Kuang, S., Laskin, J. (2020). Imaging of triglycerides in tissues using nanospray desorption electrospray ionization (Nano-DESI) mass spectrometry. International Journal of Mass Spectrometry, 448, 116269.

Huang, D., Deng, M., & Kuang, S. (2019). Polymeric carriers for controlled drug delivery in obesity treatment. Trends in Endocrinology & Metabolism, 30(12), 974-989.

Song, T., & Kuang, S. (2019). Adipocyte dedifferentiation in health and diseases. Clinical Science, 133(20), 2107-2119.

Kargl, C. K., Nie, Y., Evans, S., Stout, J., Shannahan, J. H., Kuang, S., & Gavin, T. P. (2019). Factors secreted from high glucose treated endothelial cells impair expansion and differentiation of human skeletal muscle satellite cells. The Journal of physiology, 597(20), 5109-5124.

Wang, C., Arrington, J., Ratliff, A. C., Chen, J., Horton, H. E., Nie, Y., ... & Kuang, S. (2019). Methyltransferase-like 21c methylates and stabilizes the heat shock protein Hspa8 in type I myofibers in mice. Journal of Biological Chemistry, 294(37), 13718-13728.

Huang X, Kuang S, Applegate TJ, Lin TL, Cheng HW. (2019). The development of the serotonergic and dopaminergic systems during chicken mid-late embryogenesis. Molecular and Cellular Endocrinology. 493:110472.

Patel, S. H., Yue, F., Saw, S. K., Foguth, R., Cannon, J. R., Shannahan, J. H., ..., Kuang, S., Sabbaghi, A., & Carroll, C. C. (2019). Advanced glycation end-products suppress mitochondrial function and proliferative capacity of achilles tendon-derived fibroblasts. Scientific reports, 9(1), 1-17.

Jia, Z., Nie, Y., Yue, F., Kong, Y., Gu, L., Gavin, T. P., ... & Kuang, S. (2019). A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration. Elife, 8, e47097.

Wang, C., Zhang, B., Ratliff, A. C., Arlington, J., Chen, J., Xiong, Y., ... & Kuang, S. (2019). Methyltransferase‐like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers. The FASEB Journal, 33(8), 9672-9684.

Nie, Y., Sato, Y., Garner, R. T., Kargl, C., Wang, C., Kuang, S., ... & Gavin, T. P. (2019). Skeletal muscle‐derived exosomes regulate endothelial cell functions via reactive oxygen species‐activated nuclear factor‐κB signalling. Experimental physiology, 104(8), 1262-1273.

Solfest, J. S., Nie, Y., Weiss, J. A., Garner, R. T., Kuang, S., Stout, J., & Gavin, T. P. (2019). Effects of acute aerobic and concurrent exercise on skeletal muscle metabolic enzymes in untrained men. Sport Sciences for Health, 15(2), 417-426.

Kim, K., Reid, B. A., Ro, B., Casey, C. A., Song, Q., Kuang, S., & Roseguini, B. T. (2019). Heat therapy improves soleus muscle force in a model of ischemia-induced muscle damage. Journal of Applied Physiology, 127(1), 215-228.

Vadlamani, R. A., Nie, Y., Detwiler, D. A., Dhanabal, A., Kraft, A. M., Kuang, S., ... & Garner, A. L. (2019). Nanosecond pulsed electric field induced proliferation and differentiation of osteoblasts and myoblasts. Journal of the Royal Society Interface, 16(155), 20190079.

Suarez-Trujillo, A., Chen, Y., Aduwari, C., Cummings, S., Kuang, S., Buhman, K. K., ... & Casey, T. (2019). Maternal high-fat diet exposure during gestation, lactation, or gestation and lactation differentially affects intestinal morphology and proteome of neonatal mice. Nutrition Research, 66, 48-60.

Xiong, Y., Wu, Z., Zhang, B., Wang, C., Mao, F., Liu, X., ... & Kuang, S. (2019). Fndc5 loss‐of‐function attenuates exercise‐induced browning of white adipose tissue in mice. The FASEB Journal, 33(5), 5876-5886.

Kim, K., Kuang, S., Song, Q., Gavin, T. P., & Roseguini, B. T. (2019). Impact of heat therapy on recovery after eccentric exercise in humans. Journal of applied physiology, 126(4), 965-976.

Chen, J., Wang, C., & Kuang, S. (2019). Transdifferentiation of Muscle Satellite Cells to Adipose Cells Using CRISPR/Cas9-Mediated Targeting of MyoD. In Myogenesis. Methods in Molecular Biology, 1889, 25-41.

Yu, H., Waddell, J. N., Kuang, S., Tellam, R. L., Cockett, N. E., & Bidwell, C. A. (2018). Identification of genes directly responding to DLK1 signaling in Callipyge sheep. BMC genomics, 19(1), 1-16.

Zhang, B., Zhang, J., Zhang, C., Zhang, X., Ye, J., Kuang, S., ... & Sun, X. (2018). Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling. Frontiers in pharmacology, 9, 1227.

Pal, A., Goswami, D., Cuellar, H. E., Castro, B., Kuang, S., & Martinez, R. V. (2018). Early detection and monitoring of chronic wounds using low-cost, omniphobic paper-based smart bandages. Biosensors and Bioelectronics, 117, 696-705.

Kong, Y., Cheng, L., Mao, F., Zhang, Z., Zhang, Y., Farah, E., ..., & Kuang S., Li, L, Liu, X. (2018). Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC). Journal of Biological Chemistry, 293(37), 14328-14341.

Oprescu, S. N., Horzmann, K. A., Yue, F., Freeman, J. L., & Kuang, S. (2018). Microarray, IPA and GSEA Analysis in Mice Models. Bio-protocol, 8(17).

Sadri, B., Goswami, D., Sala de Medeiros, M., Pal, A., Castro, B., Kuang, S., & Martinez, R. V. (2018). Wearable and implantable epidermal paper-based electronics. ACS applied materials & interfaces, 10(37), 31061-31068.

Liu, Z., Wang, C., Liu, X., & Kuang, S. (2018). Shisa2 regulates the fusion of muscle progenitors. Stem cell research, 31, 31-41.

Xiong, Y., Xu, Z., Wang, Y., Kuang, S., & Shan, T. (2018). Adipocyte-specific DKO of Lkb1 and mTOR protects mice against HFD-induced obesity, but results in insulin resistance. Journal of lipid research, 59(6), 974-981.

Xiong, Y., Yue, F., Jia, Z., Gao, Y., Jin, W., Hu, K., ... & Kuang, S. (2018). A novel brown adipocyte-enriched long non-coding RNA that is required for brown adipocyte differentiation and sufficient to drive thermogenic gene program in white adipocytes. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 1863(4), 409-419.

Yin, F., Xu, R., Hu, S., Zhao, K., Yang, S., Kuang, S., ... & Han, Q. (2018). Enhanced mechanical and biological performance of an extremely fine nanograined 316L stainless steel cell–substrate interface fabricated by ultrasonic shot peening. ACS Biomaterials Science & Engineering, 4(5), 1609-1621.

Gavin, T. P., Ernst, J. M., Kwak, H. B., Caudill, S. E., Reed, M. A., Garner, R. T., ..., Kuang, S., & Dohm, G. L. (2018). High incomplete skeletal muscle fatty acid oxidation explains low muscle insulin sensitivity in poorly controlled T2D. The Journal of Clinical Endocrinology & Metabolism, 103(3), 882-889.

Chen, Y., Wang, J., Yang, S., Utturkar, S., Crodian, J., Cummings, S., ... & Casey, T. (2017). Effect of high-fat diet on secreted milk transcriptome in midlactation mice. Physiological genomics, 49(12), 747-762.

Xiong, Y., Page, J. C., Narayanan, N., Wang, C., Jia, Z., Yue, F., ... & Shi, R. (2017). Peripheral neuropathy and hindlimb paralysis in a mouse model of adipocyte-specific knockout of Lkb1. EBioMedicine, 24, 127-136.

Wang, X., Yu, C., Feng, J., Chen, J., Jiang, Q., Kuang, S., & Wang, Y. (2017). Depot-specific differences in fat mass expansion in WT and ob/ob mice. Oncotarget, 8(28), 46326.

Jiang, C., Cano-Vega, M. A., Yue, F., Kuang, S., Narayanan, N., Uzunalli, G., ... & Deng, M. (2017). Dibenzazepine-loaded nanoparticles induce local browning of white adipose tissue to counteract obesity. Molecular Therapy, 25(7), 1718-1729.

Wang, C., Yue, F., & Kuang, S. (2017). Muscle histology characterization using H&E staining and muscle fiber type classification using immunofluorescence staining. Bio-protocol, 7(10).

Castro, B., & Kuang, S. (2017). Evaluation of muscle performance in mice by treadmill exhaustion test and whole-limb grip strength assay. Bio-protocol, 7(8).

Yang, X., Yang, S., Wang, C., & Kuang, S. (2017). The hypoxia-inducible factors HIF1α and HIF2α are dispensable for embryonic muscle development but essential for postnatal muscle regeneration. Journal of Biological Chemistry, 292(14), 5981-5991.

Zhang, B., Shen, Q., Chen, Y., Pan, R., Kuang, S., Liu, G., ... & Sun, X. (2017). Myricitrin alleviates oxidative stress-induced inflammation and apoptosis and protects mice against diabetic cardiomyopathy. Scientific reports, 7, 44239.

Yin, F., Yang, S., Hu, S., Kuang, S., & Han, Q. (2017). Enhanced human osteoblast cell functions by “net-like” nanostructured cell-substrate interface in orthopedic applications. Materials Letters, 189, 275-278.

Wang, C., Liu, W., Nie, Y., Qaher, M., Horton, H. E., Yue, F., ... & Kuang, S. (2017). Loss of MyoD promotes fate transdifferentiation of myoblasts into brown adipocytes. EBioMedicine, 16, 212-223.

Zhang, C., Huang, K. C., Rajwa, B., Li, J., Yang, S., Lin, H., ... & Robinson, J. P. (2017). Stimulated Raman scattering flow cytometry for label-free single-particle analysis. Optica, 4(1), 103-109.

Yue, F., Bi, P., Wang, C., Shan, T., Nie, Y., Ratliff, T. L., ... & Kuang, S. (2017). Pten is necessary for the quiescence and maintenance of adult muscle stem cells. Nature communications, 8(1), 1-13.

Wang, C., Wang, M., Arrington, J., Shan, T., Yue, F., Nie, Y., ... & Kuang, S. (2017). Ascl2 inhibits myogenesis by antagonizing the transcriptional activity of myogenic regulatory factors. Development, 144(2), 235-247.

Shan, T., Xiong, Y., & Kuang, S. (2016). Deletion of Lkb1 in adult mice results in body weight reduction and lethality. Scientific reports, 6(1), 1-9.

Nie, Y., Sato, Y., Wang, C., Yue, F., Kuang, S., & Gavin, T. P. (2016). Impaired exercise tolerance, mitochondrial biogenesis, and muscle fiber maintenance in miR‐133a–deficient mice. The FASEB Journal, 30(11), 3745-3758.

Bi, P., Yue, F., Sato, Y., Wirbisky, S., Liu, W., Shan, T., ... & Kuang, S. (2016). Stage-specific effects of Notch activation during skeletal myogenesis. Elife, 5, e17355.

Bi, P., Yue, F., Karki, A., Castro, B., Wirbisky, S. E., Wang, C., ... & Freeman, J. L. (2016). Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice. Journal of Experimental Medicine, 213(10), 2019-2037.

Shan, T., Zhang, P., Jiang, Q., Xiong, Y., Wang, Y., & Kuang, S. (2016). Adipocyte-specific deletion of mTOR inhibits adipose tissue development and causes insulin resistance in mice. Diabetologia, 59(9), 1995-2004.

Kuhlenhoelter, A. M., Kim, K., Neff, D., Nie, Y., Blaize, A. N., Wong, B. J., ... & Roseguini, B. T. (2016). Heat therapy promotes the expression of angiogenic regulators in human skeletal muscle. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 311(2), R377-R391.

Shan, T., Xiong, Y., Zhang, P., Li, Z., Jiang, Q., Bi, P., ... & Kuang, S. (2016). Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3. Nature communications, 7, 12205.

Lubecka, K., Kurzava, L., Flower, K., Buvala, H., Zhang, H., Teegarden, D., ... & Flanagan, J. M. (2016). Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity. Carcinogenesis, 37(7), 656-668.

Shan, T., Zhang, P., Xiong, Y., Wang, Y., & Kuang, S. (2016). Lkb1 deletion upregulates Pax7 expression through activating Notch signaling pathway in myoblasts. The international journal of biochemistry & cell biology, 76, 31-38.

Yue, F., Bi, P., Wang, C., Li, J., Liu, X., & Kuang, S. (2016). Conditional loss of Pten in myogenic progenitors leads to postnatal skeletal muscle hypertrophy but age-dependent exhaustion of satellite cells. Cell reports, 17(9), 2340-2353.

Jiang, C., Wang, J. H., Yue, F., & Kuang, S. (2016). The brain expressed x-linked gene 1 (Bex1) regulates myoblast fusion. Developmental biology, 409(1), 16-25.