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Lecture Schedule
PHRM 836 - FALL 2016
12:30 to 1:20 pm Lilly Hall of Life Sciences G126
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Instructor |
Date |
Day |
Special Event |
Lecture Topic |
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Aug. 23 |
Tues |
No class: Orientation |
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Post |
Aug. 25 |
Thur |
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Protein structure-function relationship: recognition (immunoglobulin), catalysis (serine proteases) |
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Post |
Aug. 30 |
Tues |
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Protein structure-function relationship: allostery (hemoglobin vs myoglobin) |
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Post |
Sept. 1 |
Thur |
Quiz 1 |
Enzyme catalysis: structural basis and energetics of transition state stabilization, substrate recognition; coenzymes |
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Post |
Sept. 6 |
Tues |
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Regulation of enzyme activity and metabolic pathways |
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Post |
Sept. 8 |
Thur |
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Therapeutic targeting of proteins I: enzyme inhibition and selectivity |
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Post |
Sept. 13 |
Tues |
Quiz 2 |
Therapeutic targeting of proteins II: protein applications |
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Post |
Sept. 15 |
Thur |
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Cytochrome P450 and nitric oxide synthases |
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Sept. 20 |
Tues |
No class |
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Post & Ashendel |
Sept. 20 |
Tues |
Exam
I 8:00 - 9:00 pm |
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Ashendel |
Sept. 22 |
Thur |
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Nucleic Acid Structure |
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Ashendel |
Sept. 27 |
Tues |
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Nucleic Acid Structure |
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Post |
Sept. 29 |
Thur |
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Transcription factor-DNA interactions |
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Post |
Oct. 4 |
Tues |
Quiz 3 |
Membrane transporters |
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Ashendel |
Oct. 6 |
Thur |
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Signal transduction |
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Oct. 11 |
Tues |
No class - Fall Break |
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Ashendel |
Oct. 13 |
Thur |
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Signal transduction |
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Ashendel |
Oct. 18 |
Tues |
Quiz 4 |
DNA replication, repair, and recombination |
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Post & Ashendel |
Oct. 20 |
Thur |
No class - Help Session |
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Post & Ashendel |
Oct. 24 |
Mon |
Exam
II 6:30 - 7:30pm |
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Ashendel |
Oct. 25 |
Tues |
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Transcription and post-transcription |
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Ashendel |
Oct. 27 |
Thur |
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Transcription and post-transcription |
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Ashendel |
Nov. 1 |
Tues |
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Translation and Post-translation; Applications in biotechnology |
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Ashendel |
Nov. 3 |
Thur |
Quiz 5 |
Advanced Carbohydrate Metabolism: Diseases and metabolism related health issues |
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Ashendel |
Nov. 8 |
Tues |
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Advanced Lipid metabolism I – Fatty acid and Triglycerides: absorption, distribution, and regulation of metabolism |
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Ashendel |
Nov. 10 |
Thur |
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Advanced Lipid metabolism I – Fatty acid and Triglycerides: drugs and disorders |
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Ashendel |
Nov. 15 |
Tues |
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Advanced Lipid metabolism II – Cholesterol: transport, metabolism, and excretion; drugs and disorders |
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Ashendel |
Nov. 17 |
Thur |
Quiz 6 |
Advanced Amino Acid metabolism: One carbon metabolism, relationship to certain vitamin deficiencies, basic clinical elements (N balance, essential amino acids and nutritional protein quality, diseases, creatine and creatinine) |
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Ashendel |
Nov. 22 |
Tues |
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Advanced Amino Acid metabolism: Specific pathways and disorders; clinical situations and protein nutrition management |
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Ashendel |
Nov. 24 |
Thur |
No class – Thanksgiving Holiday |
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Ashendel |
Nov. 29 |
Tues |
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Heme and iron metabolism and disorders |
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Dec. 1 |
Thur |
Quiz 7 |
Advanced Nucleotide metabolism: Disorders and drugs |
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Ashendel |
Dec. 6 |
Tues |
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Metabolic Interrelationships: basic macro-nutrition; BMR and activity; obesity; appetite and satiety; feed-starve cycle |
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Ashendel |
Dec. 8 |
Thur |
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Metabolic Interrelationships: metabolic syndrome, regulatory pathways, diabetes, and drugs |
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Ashendel |
Dec. 13 |
Tues |
Exam III 7:00 to 9:00 pm Lilly 1-105 |
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