Conference Papers

Dawith Lim, Zhen Hua, Zhe LI, Ali Ajrouch, Ahmad Karkash, Shadia Jalal, Michael Childress, John Turek, David Nolte. Observing cross-species cross-cancer chemosensitivity signatures with dynamic-contrast OCT. SPIE Photonics West 2024, Paper 12830-70, January 2024, San Francisco, California, United States.

Gabrial Goodwin, Dawith Lim, John Turek, David Nolte. Ultra-stable Dynamic Contrast Digital Holography of Biological Tissues. Optica Imaging Congress (3D, COSI, DH, FLatOptics, IS, pcAOP) Technical Digest Series (Optica Publishing Group, 2023), paper HTu5C.3 •https://doi.org/10.1364/DH.2023.HTu5C.3

Zhen Hua, Shadia Jalal, John Turek, David D. Nolte. Classifying tumor heterogeneity of human esophageal cancer biopsies by dynamic contrast OCT with deep learning.  Proceedings Volume 12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; 123670L (2023) https://doi.org/10.1117/12.2647602 Event: SPIE BiOS, 2023, San Francisco, California, United States

Hua, Zhen, John Turek, David Nolte. Phenotyping drug response of living tissue based on tissue-dynamics spectroscopy. SPIE BiOS. Vol 11959, Dynamics and Fluctuations in Biomedical Photonics XIX. 1195906 (2022). https://doi.org/10.1117/12.2610371

David Nolte, Ran An, and John Turek. Dynamic-Contrast Digital Holography with Deep Learning for Cancer Chemotherapy Selection. Digital Holography and Three-Dimensional Imaging 2021. Washington DC. July 19-23, 2021. ISBN: 978-1-943580-89-7. 

David Nolte, Ran An, and John Turek. Intracellular Doppler Spectroscopy and Deep Learning in Clinical Trials to Personalize Cancer Chemotherapy. European Conference on Biomedical Optics 2021. Munich Germany, June 20-24, 2021. ISBN: 978-1-943580-95-8.

Honggu Choi, Jessica Zuponcic, Eduardo Ximenes, John Turek, Michael Ladisch, David Nolte. Misuse of antibiotics causes bacteria to develop antibiotic-resistance. Biodynamic imaging (BDI) of living tissue infected by E. coli detects antibiotic resistance and sensitivity by treating bacterial infections with antibiotics in vitro. Conf. Lasers and Electo-Optics (CLEO), San Jose CA, May, 2020.

Honggu Choi, Jessica Zuponcic, Eduardo Ximenes, Michael Ladisch, John Turek, David Nolte. Doppler Detection of Pathogenic Activity in Living Tissue by Biodynamic Imaging. Conference on Lasers and Electro-Optics, OSA Technical Digest (Optical Society of America), 2019.

David D. Nolte, John J. Turek, Daniela E. Matei, Shadia Jalal, Dopper imaging of intracellular dynamics in clinical cancer chemotherapy, Proc. SPIE 11073, Clinical and Preclilnical Optical Diagnostics II, 110730J 19 July 2019); https://doi.org/10.1117/12.2527073

John J. Turek, David D. Nolte, Ran An. Biodynamic Imaging Predicts Response of Breast Cancer Patients to Neoadjuvant Chemotherapy. American Association of Cancer Research Annual Meeting. Chicago, IL. Abstract #2849, 2018.

 David D. Nolte, Zhe Li, Honggu Choi, John Turek, and Shadia Jalal. Biodynamic 4D Imaging of Living Cancer Biopsies for Personalized Selection of Chemotherapy. Clinical and Translational Biophotonics. Hollywood, Florida. April 3-6, 2018. ISBN: 978-1-943580-41-5.

Nolte, David D.; Li, Zhe; Choi, Honggu; Childress, Michael; Turek, John; Jalal, Shadia. Intracellular Doppler Imaging Clinical Trials in Personalized Cancer Care. 2018. CLEO: Applications and Technology, Paper# ATu4J.6

M J Kanis, D. Merrill, W. Swetziga, H. Cardenas, J. Kima, D. Matei, J. Turek and D. Nolte. A pilot study evaluating biodynamic imaging (BDI) as a novel method in predicting response to chemotherapy in ovarian cancer. Soc. for Gynecologic Oncology. March 2017.

Zhe Li, John J Turek, David D Nolte. Common-path biodynamic imaging for dynamic fluctuation spectroscopy of 3D living tissue. SPIE BIOS DOI: 10.1117/12.2251439. March 2017.

Zhe Li, Honggu Choi, Shadia Jalal, John J Turek, David D. Nolte. Biodynamic 4D Imaging of Living Cancer Biopsies for Personalized Selection of Chemotherapy. Clinical and Translational Biophotonics. Dec 2017. DOI 10.1364/TRANSLATIONAL.2018.CTu4B.7.


Gayatri, Narayanan, David D. Nolte, Daniela Matei, Ran An, John J. Turek. Investigation of MDR1 in ovarian cancer using biodynamic imaging. American Association for Cancer Research Annual Meeting, Washington DC Abstract 2046. . (4/07/2017).

Daniel Merrill, Hao Sun, Bakhtiyor Yakubov, Daniela Matei, John Turek and David Nolte, Heterogeneous response to platinum in metastatic ovarian cancer detectable by biodynamic imaging, American Association for Cancer Research Annual Meeting, New Orleans, Louisiana. (4/18/2016)

Hao Sun, Daniel Merrill, John Turek, David Nolte, “Biodynamic profiling of three-dimensional tissue growth techniques,” Proc. SPIE 9707, Dynamics and Fluctuations in Biomedical Photonics XIII, 97070S (17 March 2016)

John J. Turek, Dan Merrill, Michelle Custad, Michael Childress, Ran An, Bakhtiyor Yakubov, David D. Nolte, Daniela Matei.  Novel Intracellular Doppler Imaging Predicts Therapeutic Efficacy for Personalized Medicine.  American Association for Cancer Research, Philadephia, PA, April, 2015.

Daniel A. Merrill, Ran An, John Turek, David Nolte. Role of cellular adhesions in tissue dynamics spectroscopy. Photonics West.  Proceedings Volume 8942, March 2014.

Nolte, David D.; An, Ran; Childress, Michael; Turek, John. Biodynamic 3D Imaging for Personalized Cancer Care. 2014. CLEO: Applications and Technology, Paper# ATh1O.6

Turek, John, Ran An, Daniela Matei, Mike Childress, David Nolte. Personalized Therapy Assessment using Biodynamic Imaging to Predict Chemotherapeutic Efficacy. Society for Laboratory Automation and Screening, San Diego, January, 2014.

Ran An, John Turek, Zoltan Machaty, David Nolte. Motility Contrast Imaging of Live Porcine cumulus-oocyte complexes. Photonics West. Proceedings Volume 8593, March 2013.

Turek, John, Ran An, Daniela Matei, David Nolte. Tissue Dynamics Imaging to Predict Drug Therapeutic Response in Cancer Patients. Association for Clinical and Translational Science, Washington, DC, April 2013.

Turek, John, Ran An, Daniela Matei, David Nolte. Three-Dimensional Tissue Dynamics Imaging for Drug Discovery and Personalized Medicine. Society for Laboratory Automation and Screening. Orlando, January 2013.

Ran An, Kwan Jeong, John Turek, David Nolte. Label-free mitosis detection in tumor spheroids using tissue dynamics imaging. Proc. SPIE 8230:1-9, February 2012.

Ran An, Kwan Jeong, John Turek, David Nolte. Identifying mitosis deep in tissue using dynamic light scattering fluctuation spectroscopy. Proc. SPIE 8222:1-8, February 2012.

Ran An, Kwan Jeong, John J Turek, David Nolte. The Role of Cellular Environment in Dynamic Light Scattering. Proc. SPIE -The International Society for Optical Engineering. 7907. January 2011. DOI 10.1117/12.874855

Turek, John, Living Motion as Label-Free Imaging Contrast in Three-Dimensional Tissue-Based Drug Screening, Biomedical Optics (BIOMED) 2010.

Nolte, David D; Jeong, Kwan; Turek, John J, Phase-Sensitive Motility Imaging of Tumor Response to Drugs in Digital Holography, Digital Holography and Three-Dimensional Imaging (DH) 2010.

David D. Nolte and John Turek, Three-Dimensional Speckle Holography of Cellular Motion inside Tissue. Proc. of SPIE-OSA Biomedical Optics, SPIE Vol. 7371, 737102,  2009.

D. D. Nolte and J. Turek, Motility Contrast Imaging: Digital Holography of Cellular Motion in 3D Tissues, OSA Topical Meeting on Digital Holography, Vancouver, Canada, April 26-29 (2009)

D. D. Nolte, K. Jeong and J. Turek, Fluctuation Spectroscopy in Low-Coherence Dynamic Light Scattering of Tissue Responding to Pharmacologicals, SPIE Photonics West, San Jose, CA Jan. 23 - 28 (2009)

K. Jeong, D. D. Nolte and J. J. Turek, Cellular Motion as Contrast Agent in Tumor Imaging, OSA Conf. Lasers and Electrooptics, Baltimore, MD, May 7-11 (2007)

 Nolte, David D; Jeong, Kwan; Turek, John J, Digital Holographic Optical Coherence Imaging: 3-D Motility Assays of the Effect of Anticancer Drugs. Photorefractive Effects, Photosensitivity, Fiber Gratings, Photonic Materials and More (PR) 2007.

Jeong K., D. D. Nolte, J. J. Turek, Functional imaging by dynamic speckle in digital holographic optical coherence imaging, Photonics West, San Jose CA, Jan. 22-26 (2007)

Jeong, Kwan; Nolte, David D; Turek, John J, Adaptive Compensation of Multiply Scattered Light in Photorefractive Holography of Living Tissue. Conference on Lasers and Electro-Optics (CLEO) 2006.

 Kwan Jeong, J. J. Turek and D. D. Nolte, Functional Optical Coherence Imaging of Tumor Response to a Metabolic Electron Transport Inhibitor, SPIE Photonics West Conference, San Jose Ca, Jan. 22-27 (2006)

Jeong, K., D.D. Nolte, and J.J. Turek. Digital holographic optical coherence imaging of tumor tissue. SPIE Photonics West, 2006.

Jeong, K., D.D. Nolte, and J.J. Turek. Functional optical coherence imaging of tumor response to pharmacological agents. SPIE Photonics West, 2006.

Jeong, Kwan; Turek, John J; Nolte, David D,  Biomedical Functional Imaging of Tissue in Coherence-Domain Speckle Holography. Photorefractive Effects, Materials, and Devices (PEMD) 2005

Kwan Jeong, John J. Turek and David D. Nolte, Phase-Contrast Optical Coherence Imaging of Tissue, Photonics West, San Jose, CA Jan. 26 (2005)

Jia,Y and J.J. Turek. Inducible nitric oxide synthase links NF-kB to PGE2 in fibroblast in-vitro wound healing. Experimental Biology, San Diego, CA  2005.

K. Jeong, M. Mustata, D.D. Nolte, John Turek. Fourier-domain holographic optical coherence imaging. Conf. Lasers and Electo-Optics (CLEO), San Francisco CA, May 16-21, 2004.

D. D. Nolte, P. Yu and J. J. Turek, Physical basis of holographic optical coherence imaging of living tissue, Photonics West, Jan. 24-29, 2004.

David D. Nolte, Kwan Jeong, Mirela Mustata, Ping Yu, John Turek. Holographic optical coherence imaging of living tissue. Conf. Lasers and Electo-Optics (CLEO), San Francisco CA, May 16-21, 2004.

K. Jeong, M. Mustata and D. D. Nolte, J. J. Turek, Fourier-domain holographic optical coherence imaging, Biomedical Optics Conference, Miami FL, April 14-17, 2004.

Jia, Y. and J.J. Turek. Effects of polyenoic fatty acids on collagen formation related to prostaglandin E and different receptor subtypes activities in 3T3-Swiss fibroblasts. Experimental Biology, Washington D.C., 2004.

Nolte, D.D., P.Yu, J. Turek. Shimmering holograms and cellular motion in osteogenic tumors. Proceedings of SPIE Vol. 5140. European Conference on Biomedical Optics, Munich, Germany, June 22-23, 2003.

P. Yu, D. D. Nolte, J. Turek, M. R. Melloch, C. Dunsby, Y. Gu and P.M.W. French, Imaging of Internal Tumor Necroses using Full-Frame Optical Coherence Imaging, Biological Optics Symposium, Photonics West, San Jose Jan 27-31 (2003)

P. Yu and D. D. Nolte, J. J. Turek and M. R. Melloch, Shimmering Holograms and the Measure of Life in Optical Coherence Imaging of Tumor Spheroids, Conf. Lasers and Electro-Optics, Baltimore June 2-6, 2003.

P. Yu, J. J. Turek, P. M. W. French, M. R. Melloch and D. D. Nolte, Shimmering Holograms and the Measure of Health inside Rat Tumors, Ninth International Conference on Photorefractive Effects, Materials, and Devices: Self-developing and dynamic holographic materials, La Colle sur Loup, Nice, France, June 17 - June 21, 2003.

Turek, J. J. and I. A. Schoenlein. Altered gene expression in 3T3 fibroblasts enriched with different polyunsaturated fatty acids. Purdue University, Dept. of Basic Medical Sciences, W. Lafayette IN, 47907. Experimental Biology 2002, New Orleans, LA.

Walker, R., P.Mitchell, K. Hannon, J. Turek. 3-D quantitation of the effects of FGF-5 on development of the ischium in chick embryos. Purdue University. W. Lafayette IN, 47907. Experimental Biology, New Orleans, LA April 19-25, 2002

J. Chino, P. Yu, G.-M. Mustata, P. M. W. French, D. Nolte, J. Turek. 3D visualization of tumor spheroids for correlative microscopy of video hologram images.  Purdue University. W. Lafayette IN, 47907, Imperial College of Science, Technology, and Medicine, London, England. Experimental Biology, New Orleans, LA April 19-25, 2002.

P.Yu, M.Mustata, W.Headley, D.D.Nolte and J. J. Turek. Noninvasive Optical Imaging of Necrosis inside Tumor Spheroids,  BIOS 2002, SPIE International Symposium on Biomedical Optics, San Jose, CA Jan. 19-25, 2002.

P.Yu, M.Mustata, W.Headley, D.D.Nolte and J. J. Turek. Application of Photorefractive Multiple Quantum Wells to Biological Imaging, 8th Int. Conf. on Photorefractive Effects, Materials and Devices, Delavan, Wisconsin July 8-12, 2001.

P. Yu, W. Headley, and D. D. Nolte, J. J. Turek and P. M. W. French. Optical coherence imaging of tumor spheroids, Conf. on Lasers and Electro-Opt., May 9, 2001.

Turek J.J.  Dietary lipids and immune function. American Oil Chemists Society. Minneapolis, MN, May 13-16, 2001.

Turek, J.J. S.P. Massimino, K.P. Boebel, and M.G. Hayek. Investigation of garlic as an immunomodulator in canines. In Reinhart GA, Carey D.P. eds. Recent Advances in Canine and Feline Nutrition, Vol III: Iams International Nutrition Symposium Proceedings. Wilmington:Orange Frazer Press, pages 573-582, 2000. 

Turek, J.J. B.A. Watkins, I.A. Schoenlein, M.G. Hayek, C.G. Aldrich. Ingestion of oxidized lipids alters canine antioxidant status and immune function. In Reinhart GA, Carey D.P. eds. Recent Advances in Canine and Feline Nutrition, Vol III: IamsInternational Nutrition Symposium Proceedings. Wilmington:Orange Frazer Press, pages 541-553, 2000. 

Watkins, B.A., J.J. Turek, A.J. Lepine, M.F. Seifert, and G.A. Reinhart. Influence of polyunsaturates on bone modeling and health. In Reinhart GA, Carey D.P. eds. Recent Advances in Canine and Feline Nutrition, Vol III: Iams International Nutrition Symposium Proceedings. Wilmington:Orange Frazer Press, pages 467-480, 2000.

Watkins, B.A., J.J. Turek, A.J. Lepine, C.G. Aldrich, M.G. Hayek. Relationships of fat quality and antioxidants in bone and cartilage. In Reinhart GA, Carey D.P. eds. Recent Advances in Canine and Feline Nutrition, Vol III: Iams International Nutrition Symposium Proceedings. Wilmington:Orange Frazer Press, pages 505-514, 2000.

Hankenson, K.D., B.A. Watkins, I.A. Schoenlein, K.G.D. Allen, J.J. Turek. Arachidonic acid and eicosapentaenoic acid (EPA) improve medial collateral ligament fibroblast wound healing but only EPA enhances collagen formation and alters interleukin-6 production. Experimental Biology, Washington D.C., 1999.

Mathias, C.J. J.J. Turek, D.J Waters, P.S. Low, M.A. Green. Autoradiographic study of regional and In-111-DTPA-folate distribution in tumor and kidney using an athymic mouse KB tumor model. 11th International Symposium on Radiopharmacology. St. Louis MO., June 24-27, 1999.

Turek, JJ, BA Watkins, IA Schoenlein, MG Hayek, CG Aldrich. Ingestion of oxidized lipids alters canine anti-oxidant status and immune function. Nutritional immunology symposium. 16th Annual Meeting American College of Veterinary Internal Medicine. San Diego, CA 1998.

Turek, J.J. and MG Hayek. Effect of Omega-6:Omega-3 Fatty Acid Ratios on Cytokine Production in Adult and Geriatric Dogs. In Reinhart GA, Carey D.P. eds. Recent Advances in Canine and Feline Nutrition, Vol II: 1998. Iams Nutrition Symposium Proceedings. Wilmington:Orange Frazer Press, 1998; 305-324.

Hayek, M.G., J.J. Turek, G.A. Reinhart, and J.D. Burr. Effect of age, breed and dietary omega-6(n-6):omega-3(n-3) fatty acid ratio on IL-1, IL-6, TNF-alpha production and serum fatty acid profiles in the dog. Experimental Biology, San Francisco, CA 1998.

Leclerc,L.A., J.J. Turek, K.D.G. Allen, and B.A. Watkins. Linoleic acid impairs but beta-carotene may protect chondrocyte function. Experimental Biology, San Francisco, CA 1998.

Watkins, B.A., J.J. Turek, J. Steenbergen, Y.Li, L. Kanach, M.G. Hayek, and C.G. Aldrich. Effects of dietary oxidized lipid on bone metabolism in dogs. Experimental Biology, San Francisco, CA 1998.

Turek, J.J., B.A. Watkins, I.A. Schoenlein, M.G. Hayek, C.G. Aldrich. Effect of dietary oxidized lipids on growth and immune function in dogs. Experimental Biology, San Francisco, CA 1998.

Mathias,C.J., S. Wang, D.J. Waters, J.J. Turek, P.S. Low, and M.A. Green. Indium-111- DTPA-folate as a radiopharmaceutical for targeting tumor-associated folate binding protein. Society of Nuclear Medicine. San Antonio, 1997.

Turek, J.J., Y. Li, I.A Schoenlein, K.G.D. Allen, and B.A. Watkins. Conjugated linoleic acid alters cytokine but not PGE2 production in rats. Experimental Biology, New Orleans, LA 1997.

Hankenson, K.D. and J.J. Turek. An in vitro comparison of the porcine ligament of the head of the femur to the anterior cruciate and medial collateral ligaments. Experimental Biology, New Orleans, LA 1997.

Guptill,L., J. Tobolski, C-C, Wu, L. Glickman, J. Turek, H. HoganEsch. Extracellular Bartonella henselae in blood of experimentally infected cats. Conference of Research Workers in Animal Disease. Chicago, IL, 1996.

Watkins, B.A., J.J. Turek, M.F. Seifert, H. Xu. Importance of Vitamin E in bone formation and in chondrocyte function. American Oil Chemists Society, Indianapolis, IN, 1996.

Bernadet, J.H., B.A. Watkins, J.J. Turek. Antioxidant nutrients vary in their effects on oxidative stress in chondrocytes. Experimental Biology. Washington D.C., 1996.

Fan, M.Z., O. Adeola, E.K. Asem, J. Turek. Preparation and characterization of porcine jejunal brush border membrane vesicles. Am. Soc. Anim. Science, Midwestern Meeting. Des Moines, IA, April, 1996.

Xu, H., B.A. Watkins, J.J. Turek. Effects of iron-induced oxidative stress on cellular injury and collagen synthesis of chondrocytes enriched with fatty acids and vitamin E. Experimental Biology. 1995.

Turek, J.J., I.A. Schoenlein. Antibiotics affect porcine alveolar macrophage function. Conference of Research Workers in Animal Disease. Chicago, 1994.

Turek, J.J., I.A. Schoenlein, L.K. Clark, and W.G. Van Alstine. Dietary fatty acid effects on porcine alveolar macrophage function. Conference of Research Workers in Animal Disease, Chicago, 1993.

Kanthasamy, A.G, J.L. Borowitz, J.J. Turek, G. Pavlakovic, and G.E. Isom. Cyanide-induced dopaminergic toxicity in mice.Society for Neuroscience. Washington, D.C. 1993.

Leamon, C.P., P.S. Low, and J.J. Turek. Cytotoxicity of folate-momordin conjugates in cultured human cells. Annual meeting Amer. Society for Cell Biology. 1992

Burkhardt, J.E., M.A. Hill, J.J. Turek, and W.W. Carlton. Characterization of difloxacin arthropathy in immature Beagle dogs. Society of Toxicologic Pathologists. Phoenix, AZ, 1992

Turek, J.J., C.P. Leamon, and P.S. Low. Endocytosis of folate labeled proteins: Ultrastructural localization in KB cells. 50th Annual Meeting Electron Microscopy Society of America, Boston, MA, 1992.

Knapp, D., T.C. Chan, D.B. Denicola, J. Turek, R. Leibnitz, L. Shaffer, P. Miller, and J. Mitchell. Development and validation of a canine natural killer cell assay. Veterinary Cancer Society Forum, Auburn, Alabama, 1990.

Salaris, S.C., J.J. Turek, C.F. Babbs. Cytochemical detection of hydrogen peroxide generation in hepatocytes. 5th biennial meeting of the International Society for Free Radical Research

Turek, J.J. and G.D. Bottoms. Effect of dietary fatty acids on tumor necrosis factor production. 1st International Congress, International Endotoxin Society. San Diego, California, 1990.

Bottoms G.D. and J.J.Turek. Effect of dietary fatty acids on endotoxin-induced eicosanoid production by rat peritoneal macrophages. 1st International Congress, International Endotoxin Society. San Diego, California, 1990.

Turek, J.J. and G.D. Bottoms. Dietary fatty acid induced changes in tumor necrosis factor-alpha (TNF-alpha) production by rat peritoneal macrophages. Am. Soc. for Cell Biol., Houston, Texas, 1989.